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Pediatr Dermatol. 2014 May-Jun;31(3):395-7. doi: 10.1111/pde.12305. Epub 2014 Mar 6.

Topical N-acetylcysteine for the treatment of lamellar ichthyosis: an improved formula.

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  • 1Department of Dermatology, Complexo Hospitaladio de Pontevedra, Pontevedra, Spain.


Topical N-acetylcysteine is gaining recognition as a useful and safe therapy for lamellar ichthyosis. We report a case of inherited lamellar ichthyosis that showed a good response to treatment with a new formula of N-acetylcysteine cream. With this new formula, which is described in the article in a practical manner, the odor of sulfur was minimized and we obtained excellent adherence to treatment.

© 2014 Wiley Periodicals, Inc.

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