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Zhong Yao Cai. 2013 Aug;36(8):1267-70.

[Non-taxoid chemical constituents from needles of Taxus cuspidata].

[Article in Chinese]

Author information

  • 1Hebei Provincial Food and Drug Inspection Institute, Shijiazhuang 050011, China.
  • 2Department of Medicinal Natural Product Chemistry, Hebei Medical University, Shijiazhuang 050017, China.

Abstract

OBJECTIVE:

To study the chemical constituents in the needles of Taxus cuspidata collected from Japan.

METHODS:

Chemical constituents were isolated by column chromatography, TLC and preparative HPLC. The structures were identified on the basis of NMR spectral analysis.

RESULTS:

Six non-taxoids were isolated and identified as: 4-[(1E)-3-hydroxy-1-buten-1-yl]-3,5,5-trimethyl-2-cyclohexen-1-one (1), megastigm-5-ene-3, 9-diol (2), 6alpha-epoxy-7-megastigmen-9-one (3), 4-(4-hydroxyphenyl)-2-butanone (4), 12-hydroxy-alpha-cyperone (5), scutellarein-7-O-alpha-L-rhamnoside (6).

CONCLUSION:

Compounds 2 - 6 are isolated from Taxus genus for the first time. Compound 1 is obtained from Taxus cuspidata for the first time.

PMID:
24558823
[PubMed - indexed for MEDLINE]
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