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Ultrasound Med Biol. 2014 Jun;40(6):1089-95. doi: 10.1016/j.ultrasmedbio.2013.12.019. Epub 2014 Feb 17.

Kupffer-phase findings of hepatic hemangiomas in contrast-enhanced ultrasound with sonazoid.

Author information

  • 1Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan. Electronic address: sugimoto@tokyo-med.ac.jp.
  • 2Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan.
  • 3Department of Radiology, Tokyo Medical University, Tokyo, Japan.
  • 4Ultrasound Division, Toshiba Medical Systems Corporation, Tochigi, Japan.

Abstract

The aim of this study was to assess quantitatively the Kupffer-phase enhancement patterns of hepatic hemangiomas in contrast-enhanced ultrasound (CEUS) with Sonazoid. A total of 46 patients with 46 hepatic hemangiomas (17.1 ± 6.2 mm in diameter, 34 typical type and 12 high-flow type) underwent CEUS in the Kupffer phase. The lesion-to-liver contrast ratio in the Kupffer phase was quantitatively assessed for both types of hemangioma. Most of the hepatic hemangiomas, whether or not they were the high-flow type, were iso- to hypo-echoic relative to the surrounding liver parenchyma. The contrast ratio was -5.33 ± 6.70 dB for the high-flow hemangiomas and -4.54 ± 6.28 dB for the typical hemangiomas. There was no significant difference in contrast ratio between the two types of lesions (p = 0.73). All of the hemangiomas, whether of typical or high-flow type, are iso- to hypo-echoic relative to the surrounding liver parenchyma on Kupffer-phase imaging.

Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

KEYWORDS:

Contrast; Hemangioma; High-flow type; Kupffer phase; Liver; Sonazoid; Ultrasound

[PubMed - indexed for MEDLINE]
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