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Catheter Cardiovasc Interv. 2014 Dec 1;84(7):1042-50. doi: 10.1002/ccd.25455. Epub 2014 Mar 11.

Extended follow-up following "full-metal jacket" percutaneous coronary interventions with drug-eluting stents.

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  • 1Interventional Cardiology Unit, EMO-GVM Centro Cuore Columbus, Milan, Italy.

Abstract

OBJECTIVES:

To report very long-term follow-up of "Full-Metal Jacket" (FMJ) percutaneous coronary interventions (PCI) in long-diffuse coronary lesions with drug-eluting stents (DES).

BACKGROUND:

PCI for long-diffuse lesions may result in FMJ, which is not preferred by some operators due to long-term risk of restenosis and stent thrombosis. The data on long-term follow-up of patients with FMJ are limited and would be useful in understanding the safety and feasibility of such a strategy.

METHODS:

Between April 2002 and March 2007, 274 patients (297 lesions in native coronary arteries) underwent PCI utilizing DES. FMJ was described as lesions requiring ≥ 60 mm of continuous stent. The measured endpoints were cardiac death, target-vessel myocardial infarction (MI), target lesion revascularization (TLR), target-vessel revascularization (TVR), and major adverse cardiac events (MACE) defined as composite of cardiac death, target-vessel MI, and TVR.

RESULTS:

The mean age of patients was 62.1 ± 11 years. The mean length of total stents used was 75.1 ± 16.4 mm (60-150). During the median follow-up of 74.7 months (interquartile range: 58-96), the rates of cardiac death, MI, TLR, and TVR were: 5.8% (n = 16), 6.2% (n = 17), 27.3% (n = 81), and 30% (n = 89), respectively. The MACE rate was 34%. Definite and probable stent thrombosis occurred in 10 patients (3.6%).

CONCLUSION:

The long-term follow-up of patients with FMJ is acceptable especially in regards to hard endpoints (death and MI) given the complexity of lesions treated. The high MACE rate was driven mainly by TVR. The availability of newer-generation DES and bioabsorbable scaffolds may improve these results. © 2014 Wiley Periodicals, Inc.

© 2014 Wiley Periodicals, Inc.

KEYWORDS:

drug-eluting stents; full-metal jacket; long-diffuse lesions

PMID:
24550090
[PubMed - in process]
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