Temperature-controlled release by changes in the secondary structure of peptides anchored onto mesoporous silica supports

Chem Commun (Camb). 2014 Mar 25;50(24):3184-6. doi: 10.1039/c3cc49421g. Epub 2014 Feb 12.

Abstract

Changes in the conformation of a peptide anchored onto the external surface of mesoporous silica nanoparticles have been used to design novel temperature-controlled delivery systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Models, Molecular
  • Nanoparticles / chemistry
  • Particle Size
  • Peptides / chemistry*
  • Porosity
  • Protein Structure, Secondary
  • Silicon Dioxide / chemistry*
  • Surface Properties
  • Temperature*

Substances

  • Peptides
  • Silicon Dioxide