Schweiz Arch Neurol Psychiatr. 1988;139(1):31-8.

[Primary lymphoma of the nervous system following radiculoneuritis caused by Borrelia burgdorferi: study of a case].

[Article in French]

Source

Centre Hospitalier Universitaire Vaudois, Lausanne Service de Neurologie.

Abstract

A 50-year-old man had a primary lymphoma of the central nervous system one year after a tick bite and a radiculoneuritis secondary to Borrelia burgdorferi infection. Determination of antibodies against Borrelia burgdorferi revealed increasing IgM and IgG titers, and the autopsy showed a primary B-cell immunoblastic lymphoma of the brain without evidence of extraneural lymphoproliferative disorder. Lymphoma of the brain is a rare type of central nervous system cancer, and sporadic cases appear without predisposing features such as immunosuppression or viral infection. The controversy surrounding the histogenesis of this neoplasm is reviewed: an unknown agent or a cofactor should provoke cellular proliferation and the formation of a lymphoma.

PMID:: 2451279; [PubMed - indexed for MEDLINE]

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Immunoglobulin M

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