Format

Send to:

Choose Destination
See comment in PubMed Commons below
Carbohydr Res. 2014 Mar 11;386:62-7. doi: 10.1016/j.carres.2013.11.013. Epub 2013 Dec 1.

Structural elucidation of the capsular polysaccharide from Streptococcus pneumoniae serotype 47A by NMR spectroscopy.

Author information

  • 1Carlsberg Laboratory, 10 Gamle Carlsberg Vej, 1799 Copenhagen V, Denmark. Electronic address: Bent.Petersen@carlsberglab.dk.
  • 2Carlsberg Laboratory, 10 Gamle Carlsberg Vej, 1799 Copenhagen V, Denmark.
  • 3Farmas√łytisk insitutt, Sem Selands vei 3, 0316 Oslo, Norway.
  • 4Statens Serum Institut, 5 Artillerivej, DK-2300 Copenhagen S, Denmark.

Abstract

The structure of the serotype 47A (Danish nomenclature system) capsular polysaccharide from Streptococcus pneumoniae was elucidated by NMR spectroscopy. The following structure of the repeating heptasaccharide was deduced: [structure: see text]. The serotype 47A capsular polysaccharide is one of 91 structurally and serologically distinct capsular polysaccharides that have been recognized in S. pneumoniae, a significant human pathogenic bacterium and model system in medical microbiology. Structure and NMR spectra are compared to previously solved capsular polysaccharide structures of other serotypes.

Copyright © 2013 Elsevier Ltd. All rights reserved.

KEYWORDS:

Capsular polysaccharide; NMR structual assignment; Serotype 47A; Streptococcus pneumoniae

PMID:
24486982
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk