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Eur J Clin Pharmacol. 1987;33(2):127-31.

Clinical effects of intravenous iloprost in patients with intermittent claudication.

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  • 1Department of Internal Medicine, University of Heidelberg, Germany.


In a randomized patient-blind study iloprost or hydroxy-ethyl starch 200/0.5 were given i.v. 5 h daily for 2 weeks to 24 patients suffering from severe intermittent claudication due to peripheral vascular disease. An increase in pain-free walking distance of more than 50% occurred in 6 of 11 patients after the iloprost infusions and in 7 of 12 patients after HES treatment. No significant effects on haemodynamic or clinical chemistry tests were observed.

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