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Genome Biol. 2014 Jan 27;15(1):204. doi: 10.1186/gb4154.

To be or not to be a piRNA: genomic origin and processing of piRNAs.

Abstract

Piwi-interacting RNAs (piRNAs) originate from genomic regions dubbed piRNA clusters. How cluster transcripts are selected for processing into piRNAs is not understood. We discuss evidence for the involvement of chromatin structure and maternally inherited piRNAs in determining their fate.

PMID:
24467990
[PubMed - in process]
PMCID:
PMC4053809
[Available on 2015/1/27]
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