Comparison of rates of and charges from pregnancy complications in users of extended and cyclic combined oral contraceptive (COC) regimens: a brief report

Contraception. 2014 May;89(5):396-9. doi: 10.1016/j.contraception.2013.12.006. Epub 2013 Dec 26.

Abstract

Objective: To evaluate pregnancy complication rates and related charges in users of 84/7, 21/7 and 24/4 combined oral contraceptives (COCs).

Study design: Data were obtained from the i3 InVision Data Mart™ retrospective claims database. Subjects were aged 15-40 years, first prescribed a COC between 1/1/2006 and 4/1/2011 and continuously insured for ≥1 year. 84/7 users were matched 1:1 to 21/7 and 24/4 users.

Results: Pregnancy-related complication rates and associated charges were significantly lower with 84/7 vs. 21/7 and 24/4 regimens.

Conclusion: Preliminary data suggest 84/7 regimens may be associated with fewer pregnancy complications and lower related charges.

Keywords: 84/7, 21/7, 24/4 regimens; Hormonal contraception; Pregnancy rates.

Publication types

  • Comparative Study
  • Observational Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Contraceptives, Oral, Combined / administration & dosage*
  • Fees and Charges / statistics & numerical data
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications / economics
  • Pregnancy Complications / epidemiology*
  • Retrospective Studies
  • United States / epidemiology
  • Young Adult

Substances

  • Contraceptives, Oral, Combined