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J Int Oral Health. 2013 Dec;5(6):72-7. Epub 2013 Dec 26.

Evaluation and correlation of serum lipid profile in oral and gastrointestinal cancer patients.

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  • 1Department of Oral Pathology & Microbiology, St. Joseph Dental College & Hospital, Duggirala, Eluru, Andhra Pradesh, India.

Abstract

BACKGROUND:

High or low cholesterol levels can be perturbing. High cholesterol levels in the blood are associated with increased risk of coronary heart disease whereas insinuation of decreased cholesterol levels remains imprecise. Present study is to evaluate any relationship between the serum lipid levels and the cancer. The purpose of this study is to evaluate the alteration of serum lipid profiles in untreated mucosal cancer patients.

MATERIALS & METHODS:

The study sample consisted of thirty subjects (Group I - 10 gastrointestinal cancer patients, Group II - 10 oral cancer patients and Group III - 10 controls). Fasting lipid profile of blood was evaluated using spectrophotometric kits, with CHOD PAP technique. The values obtained were then statistically analyzed using ANOVA and student 't' test.

RESULTS:

Between Group I and II, Group I comparatively showed more decrease in TC, TG, VLDL and increase in HDL & LDL. P value was significant in only TG. Between Group II and III, TC, HDL and LDL were decreased whereas TG and VLDL were increased in Group II when compared to Group III. TG, LDL, VLDL showed significant p values. Between Group I and III, the variables showed similar results as seen between Group II and III but only LDL showed significant p value. Among the three groups, only LDL showed significant p value (0.048). TC, TG, HDL and VLDL showed non - significant p values.

CONCLUSION:

Lower levels of lipid should arouse suspicion for cancer and necessary screening should be done. How to cite this article: Srinivas GV, Namala S, Ananthaneni A, Puneeth HK, Devi BS. Evaluation and Correlation of Serum Lipid Profile in Oral and Gastrointestinal Cancer Patients. J Int Oral Health 2013; 5(6):72-7 .

KEYWORDS:

High density; lipoprotein; low density lipoprotein; total cholesterol; triglycerides; very low density lipoprotein.

PMID:
24453448
[PubMed]
PMCID:
PMC3895721
Free PMC Article
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