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BMJ Case Rep. 2014 Jan 20;2014. pii: bcr2013202259. doi: 10.1136/bcr-2013-202259.

Surgical therapy of a large pancreatic solid-pseudopapillary neoplasm during pregnancy.

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  • 1Department of Surgery, Dalhousie University, Halifax, Canada.


Solid-pseudopapillary neoplasms (SPNs) of the exocrine pancreas are rare, accounting for only 2% of pancreatic tumours. These tumours predominantly affect women during the second and third decades of life. They frequently present with vague symptoms and can pose a diagnostic challenge. Surgical resection remains the treatment of choice that can cure up to 95% of patients when negative resection margins are obtained. SPNs diagnosed during pregnancy are exceptional and with profound implications on the mother and fetus. The authors present a case of an asymptomatic SPN in a 24-year-old woman diagnosed at 14 weeks of gestation on a routine prenatal ultrasound. Distal pancreatectomy, splenectomy and cholecystectomy were successfully performed at 18 weeks of gestation. A healthy full-term male child was born 5 months following surgery without complications.

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