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Int Surg. 2014 Jan-Feb;99(1):48-51. doi: 10.9738/INTSURG-D-13-00061.1.

Retroperitoneal liposarcoma with leiomyosarcomatous differentiation.

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  • 11 Department of Surgery, Social Insurance Gunma Chuo General Hospital, Gunma, Japan.

Abstract

We herein describe a 60-year-old Japanese man with a giant retroperitoneal liposarcoma undergoing leiomyosarcomatous differentiation. He was admitted to our hospital because of a 5-month history of dysphagia and abdominal distention. Abdominal computed tomography showed a giant tumor that occupied the entire retroperitoneal space. The majority of the mass was lipomatous and low density; both a heterogenous and solid mass were also present. A giant retroperitoneal liposarcoma was diagnosed, and tumor resection was performed. At surgery, the tumor was mostly isolated from the retroperitoneum and other organs. Histopathologically, the tumor comprised well-differentiated and dedifferentiated liposarcoma with heterologous differentiation of the leiomyosarcomatous components, which is a rare phenomenon in liposarcoma. The patient was alive 3 years after the first treatment, although he has had 3 local recurrences (approximately one recurrence yearly) and has been treated by repeated resection and radiotherapy.

PMID:
24444269
[PubMed - in process]
PMCID:
PMC3897341
Free PMC Article
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