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J Med Assoc Thai. 2013 Nov;96(11):1518-22.

Autologous chondrocyte implantation for cartilage injury treatment in Chiang Mai University Hospital: a case report.

Author information

  • 1Department of Orthopedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • 2Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • 3Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
  • 4Blood Bank Unit, Chiang Mai University Hospital, Chiang Mai, Thailand.

Abstract

Autologous chondrocyte implantation (ACI) has become one of the standard procedures for articular cartilage defect treatment. This technique provides a promising result. However the procedural process requires an approach of several steps from multidisciplinary teams. Although the success of this procedure has been reported from Srinakharinvirot University since 2007, the application of ACI is still limited in Thailand due to the complexity of processes and stringent quality control. This report is to present the first case of the cartilage defect treatment using the first generation-ACI under Chiang Mai University's (CMU) own facility and Ethics Committee. This paper also reviews the process of biotechnology procedures, patient selection, surgical, and rehabilitation techniques. The success of the first case is an important milestone for the further development of the CMU Human Translational Research Laboratory in near future.

PMID:
24428104
[PubMed - indexed for MEDLINE]
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