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J Oral Maxillofac Res. 2010 Oct 1;1(3):e6. doi: 10.5037/jomr.2010.1306. eCollection 2010.

Gingival squamous cell carcinoma: a case report.

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  • 1Department of Biosciences and Oral Diagnosis, São José dos Campos Dental School, São Paulo State University - UNESP, São José dos Campos, São Paulo Brazil.
  • 2São Paulo State University - UNESP, São José dos Campos Dental School, Postgraduation Program in Oral Biopathology, São José dos Campos, São Paulo, Brazil and Federal University of ABC, Postgraduation Program in Nanosciences and Advanced Materials, Santo André, São Paulo Brazil.
  • 3Department of Social Science and Pediatric Dentistry, São José dos Campos Dental School, São Paulo State University - UNESP, São José dos Campos, São Paulo Brazil.



Squamous cell carcinoma is a malignant epithelial neoplasm characterized by variable clinical manifestations. When located in the gingiva, this neoplasm may mimic common inflammatory lesions. The aim of this study was to report a case of atypical squamous cell carcinoma, in which the patient had no risk factors for the development of this neoplasm.


A 61 year old Caucasian female was seen with a 3 month history of a rapidly growing, painful nodule in the gingiva adjacent to tooth #11. Clinical examination revealed a proliferative lesion in the vestibular marginal gingiva of teeth #11 and #12, presenting with purulent exudation. Thus, in view of the clinical symptoms and differential diagnosis of an infectious granulomatous process and malignant neoplasm, an incisional biopsy was obtained from the lesion.


The diagnosis of squamous cell carcinoma was made and fourteen days after incisional biopsy, healing was found to be unsatisfactory. The patient was referred for treatment consisting of surgical excision of the tumour. A removable partial denture was fabricated for rehabilitation, one month after surgery of the maxilla; the patient was submitted to dissection of the regional lymph nodes and radiotherapy for an additional 3 months. Three years after the end of treatment, the patient continues to be followed-up and does not show any sign of recurrence.


Gingival squamous cell carcinoma is a condition which chance of cure is higher when carcinomatous lesions are diagnosed and treated early. In this instance dentists play an important role in early detection of gingival squamous cell carcinoma.


early detection of cancer.; gingival neoplasms; gingival recession; oral cancer; squamous cell carcinoma

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