Arch Int Physiol Biochim. 1986 Dec;94(5):339-48.

Human plasma lipofuscin melanins formed from tryptophan metabolites.

Hegedus ZL, Frank HA, Altschule MD, Nayak U.

Abstract

Incubation of human plasma with the tryptophan metabolites 3-hydroxy-DL-kynurenine (3HK) or 3-hydroxyanthranilic acid (3HAA) yields soluble brown pigments with the fluorescence spectrophotometric and paper chromatographic properties of plasma lipofuscin (PL). An alternative to the recognized tyrosine pathway of melanogenesis is therefore demonstrated in human plasma.

PMID:: 2440410; [PubMed - indexed for MEDLINE]

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Increased levels of serum lipofuscin derived from 3-hydroxyanthranilic acid in patients with chronic renal failure. [Arch Int Physiol Biochim. 1987]
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Human plasma lipofuscin melanins formed from tryptophan metabolites.
Human plasma lipofuscin melanins formed from tryptophan metabolites.
Arch Int Physiol Biochim. 1986 Dec ;94(5):339-48.

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Human plasma lipofuscin melanins formed from tryptophan metabolites.

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