Format

Send to:

Choose Destination
See comment in PubMed Commons below
PLoS One. 2013 Dec 20;8(12):e83774. doi: 10.1371/journal.pone.0083774. eCollection 2013.

Subjective cognitive complaints in schizophrenia: relation to antipsychotic medication dose, actual cognitive performance, insight and symptoms.

Author information

  • 1Institute of Psychology, Health and Society, University of Liverpool, Liverpool, United Kingdom.
  • 2School of Psychological Sciences, University of Manchester, Manchester, United Kingdom.
  • 3Division of Health Research, Lancaster University, Lancaster, United Kingdom.

Abstract

BACKGROUND:

Subjective cognitive complaints are prevalent in those affected by functional psychoses and a variety of possible associated factors have been investigated. However, few studies have examined these potential factors within single studies or analyses.

METHODS:

Patients with a history of a schizophrenia spectrum disorder (nā€Š=ā€Š115) and a non-clinical comparison group (nā€Š=ā€Š45) completed the Subjective Scale to Investigate Cognition in Schizophrenia (SSTICS) and the Brief Assessment of Cognition in Schizophrenia (BACS). The patient group also completed the Positive and Negative Syndromes Scale (PANSS), the Birchwood Insight Scale (IS), and the Hospital Anxiety and Depression Scale (HADS).

RESULTS:

The BACS and SSTICS scores were associated in the non-clinical comparison group, but not in the patient group. In the patient group worse subjective cognition was associated positively with good insight, greater dysphoria and greater positive symptoms. Linear regression revealed that, once other variables had been accounted for, dysphoria (HADS anxiety and depression factor) was the only significant predictor of SSTICS scores.

CONCLUSIONS:

Subjective cognitive impairment in patients with psychosis in the absence of formal testing should not be taken as evidence of impaired cognitive functioning. Mood should be investigated when patients present with subjective cognitive complaints.

PMID:
24376745
[PubMed - indexed for MEDLINE]
PMCID:
PMC3869800
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Public Library of Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk