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Ann Vasc Surg. 2014 Feb;28(2):338-44. doi: 10.1016/j.avsg.2013.04.023. Epub 2013 Dec 17.

Association of sex with long-term outcomes after popliteal artery aneurysm repair.

Author information

  • 1Department of Vascular Surgery, St. Antonius Hospital Nieuwegein, Nieuwegein, The Netherlands. Electronic address: r.kropman@antoniusziekenhuis.nl.
  • 2Department of Vascular Surgery, St. Antonius Hospital Nieuwegein, Nieuwegein, The Netherlands.
  • 3Department of Vascular Surgery, Maasstad Hospital Rotterdam, Rotterdam, The Netherlands.
  • 4Department of Radiology, St. Antonius Hospital Nieuwegein, Nieuwegein, The Netherlands.
  • 5Department of Vascular Surgery, University Medical Center, Utrecht, The Netherlands.
  • 6Department of Vascular Surgery, Catharina Hospital Eindhoven, The Netherlands.

Abstract

BACKGROUND:

We compared initial and long-term outcomes between men and women after endovascular and open repair of popliteal artery aneurysms (PAAs).

METHODS:

Between January 1993 and July 2011, 202 patients (185 men [92%]), underwent open (n = 186) or endovascular (n = 16) repair of a PAA. Data were retrospectively analyzed.

RESULTS:

Significant differences in baseline characteristics were determined between men and women with regard to aneurysm diameter (men: 30 mm [range: 14-90]; women: 26 mm [range: 13-70]; P = 0.02) and age (men: 66 ± 10 years; women: 71 ± 9 years; P = 0.05). The 30-day mortality rate was 0% in both groups. No significant differences were determined concerning 30-day complications. The median follow-up was 55 months (range: 1-121 months) in men, compared with 35 months (range: 1-183 months) in women (P = 0.74). The primary patency rates at 1, 3, and 5 years were 88%, 82%, and 76% in men compared with 64%, 64%, and 48% in women, respectively (P = 0.007). The limb salvage rates in men at 1, 3, and 5 years were 97%, 97%, and 96%, and in women were 87%, 87%, and 87%, respectively (P = 0.07). When correcting for potential confounders with multivariable regression analysis, sex was independently associated with primary patency (hazard ratio: 2.98 [95% confidence interval: 1.39-6.42]; P = 0.005).

CONCLUSIONS:

No significant differences between men and women were observed in 30-day mortality and morbidity rates after PAA repair. In the long run, women are associated with lower primary patency rates and a trend toward lower limb salvage rates compared to men.

Copyright © 2014 Elsevier Inc. All rights reserved.

PMID:
24360631
[PubMed - indexed for MEDLINE]
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