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Zhonghua Yi Xue Za Zhi. 2013 Sep 17;93(35):2820-2.

[Use of rebiopsy for clinically diagnosed metastatic lesion in patients with breast cancer].

[Article in Chinese]

Author information

  • 1Department of Oncology, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200025, China.
  • 2Comprehensive Breast Health Center, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200025. Email: kwshen@medmail.com.cn.

Abstract

OBJECTIVE:

To evaluate the roles of rebiopsy for clinically diagnosed metastatic lesion in detecting the changes of hormonal receptors and second malignancy.

METHODS:

The metastatic lesions were rebiopsied by core needle aspiration or incision in 42 patients with a clinical diagnosis of metastatic breast cancer by computed tomography or ultrasound.

RESULTS:

None of major complications occurred. Thirty-one metastases were proved pathologically. The discrepancies between primary breast cancer and metastatic lesions of estrogen receptor(ER), progesterone receptor(PR), HER-2 statuses were 22.6%, 25.8% and 9.7% respectively. And 7 second malignancies were found (16.7%, 5 primary lung and 2 primary pancreas cancers). Four patients showed no relapse through rebiopsy.

CONCLUSION:

The rebiopsy of clinically diagnosed metastatic breast cancer may find the discrepancies of ER, PR, HER-2 statuses and second malignancy so as to change the therapeutic strategies of patients.

PMID:
24360181
[PubMed - in process]
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