Two new compounds from the flowers of Rhododendron molle

Shao-Nong Chen; Guan-Hu Bao; Li-Quan Wang; Guo-Wei Qin

doi:10.1016/S1875-5364(13)60095-3

Two new compounds from the flowers of Rhododendron molle

Chin J Nat Med. 2013 Sep;11(5):525-7. doi: 10.1016/S1875-5364(13)60095-3.

Authors

Shao-Nong Chen¹, Guan-Hu Bao², Li-Quan Wang³, Guo-Wei Qin⁴

Affiliations

¹ Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; College of Pharmacy, University of Illinois at Chicago, Chicago IL, 60612, USA.
² Key Laboratory of Tea Biochemistry Biotechnology, Ministry of Education, Anhui Agricultural University, Hefei 230036, China.
³ Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
⁴ Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address: gwqin@mail.shcnc.ac.cn.

PMID: 24359778
DOI: 10.1016/S1875-5364(13)60095-3

Abstract

Aim: To study the chemical constituents of the flowers of Rhododendron molle.

Methods: Compounds were isolated by repeated chromatography over silica gel and Sephadex LH-20. Structures were elucidated based on spectral techniques, mainly 1D- and 2D-NMR and mass spectrometric analyses.

Results: Two compounds (1 and 2) were isolated.

Conclusions: Compounds 1 and 2 were identified as two new compounds: 2α, 10α-epoxy-3β, 5β, 6β, 14β, 16α-hexahydroxy-grayanane and benzyl 2, 6-dihydroxybenzoate-6-O-α-L-rhamnopyranosyl-(1→3)-β-D-glucopyranoside, respectively.

Keywords: Ericaceae; Grayanane diterpenoid; NMR spectroscopy; Rhododendrum molle.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Drugs, Chinese Herbal / chemistry*
Drugs, Chinese Herbal / isolation & purification
Flowers / chemistry*
Magnetic Resonance Spectroscopy
Molecular Structure
Rhododendron / chemistry*

Substances

Drugs, Chinese Herbal