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J Dermatolog Treat. 2015 Feb;26(1):59-62. doi: 10.3109/09546634.2013.869301. Epub 2013 Dec 20.

Successful treatment of a congenital extra-truncal vascular malformation by orally administered propranolol.

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  • 1Department of Dermatology and.


Abstract The β-blocker propranolol has become a valuable and effective drug for the treatment of infantile hemangiomas. Its therapeutic action probably results from vasoconstriction, blocking of angiogenesis through effects on vascular endothelial growth factor and induction of apoptosis. It is reasonable to suggest that propranolol can also be used effectively in the treatment of other vascular abnormalities. This case report describes propranolol treatment of vascular malformations such as Klippel-Trénaunay syndrome or Parkes-Weber syndrome in adults.


Propranolol; treatment; vascular malformation

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