Aspirin use and melanoma risk: a review of the literature

Shannon Famenini; Lorraine C Young

doi:10.1016/j.jaad.2013.09.045

Aspirin use and melanoma risk: a review of the literature

J Am Acad Dermatol. 2014 Jan;70(1):187-91. doi: 10.1016/j.jaad.2013.09.045.

Authors

Shannon Famenini¹, Lorraine C Young²

Affiliations

¹ David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California. Electronic address: sfamenini@mednet.ucla.edu.
² Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.

PMID: 24355265
DOI: 10.1016/j.jaad.2013.09.045

Abstract

In view of the increasing incidence of melanoma, it is critical to find effective preventive approaches. Contradictory evidence has been reported with regard to the possible association of aspirin use and the risk of melanoma. We review these studies and seek to elucidate the mechanism by which aspirin may produce a chemoprotective effect against melanoma.

Keywords: CI; HR; NSAID; aspirin; confidence interval; hazard ratio; melanoma; nonsteroidal anti-inflammatory drugs.

Publication types

Review

MeSH terms

Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Anticarcinogenic Agents / therapeutic use*
Aspirin / therapeutic use*
Humans
Melanoma / prevention & control*
Skin Neoplasms / prevention & control*

Substances

Anti-Inflammatory Agents, Non-Steroidal
Anticarcinogenic Agents
Aspirin