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Infect Genet Evol. 2014 Jan;21:384-90. doi: 10.1016/j.meegid.2013.12.005. Epub 2013 Dec 17.

Epidemiologic and genetic characteristics of mumps viruses isolated in China from 1995 to 2010.

Author information

  • 1National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 102206, China.
  • 2Beijing Provincial Center for Disease Control and Prevention, Beijing 100013, China.
  • 3Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
  • 4Liaoning Provincial Center for Disease Control and Prevention, Shenyang 110005, China.
  • 5Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, China.
  • 6Shannxi Provincial Center for Disease Control and Prevention, Xi'an 710054, China.
  • 7Jilin Provincial Center for Disease Control and Prevention, Changchun 130062, China.
  • 8Shanxi Provincial Center for Disease Control and Prevention, Taiyuan 030012, China.
  • 9Yunnan Provincial Center for Disease Control and Prevention, Kunming 650022, China.
  • 10Heilongjiang Provincial Center for Disease Control and Prevention, Haerbin 150030, China.
  • 11Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, China.
  • 12Sichuan Provincial Center for Disease Control and Prevention, Chengdu 610041, China.
  • 13Ningxia Provincial Center for Disease Control and Prevention, Yinchuan 750004, China.
  • 14Virus Reference Department, Public Health England, London NW9 5EQ, United Kingdom.
  • 15Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
  • 16National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 102206, China. Electronic address: wenbo_xu1@aliyun.com.

Abstract

The epidemiologic and genetic characteristics of mumps viruses detected in China from 1995 to 2010 were analyzed in this study. Mumps remains endemic in China with a high overall incidence rate. The incidence of mumps in Western China was higher than that in other regions of the country. Each year, most of mumps cases occurred between April and July, but a small peak also occurred in November and December. Mumps cases primarily affected the under 15 year old age group. Virologic data demonstrated that genotype F was the predominant circulating genotype throughout China for at least 15 years and no other genotype was detected between 1995 and 2010. Analysis of sequence data from the small hydrophobic (SH) gene indicated that multiple transmission chains of genotype F were found in various provinces of China, with no apparent chronologic and geographic restriction. This is the first report describing the epidemiology of mumps and genetic characterization of mumps viruses at the national level in China.

Copyright © 2013 Elsevier B.V. All rights reserved.

KEYWORDS:

Epidemiology; Genetic characteristics; Mumps virus

[PubMed - indexed for MEDLINE]
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