Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Clin Nurs. 2014 Jul;23(13-14):1970-7. doi: 10.1111/jocn.12442. Epub 2013 Dec 20.

Self-rated health mediates the association between functional status and health-related quality of life in Parkinson's disease.

Author information

  • 1Graduate School Kosice Institute for Society and Health, Faculty of Medicine, Safarik University, Kosice, Slovak Republic; Institute of Public Health, Department of Social Medicine, Faculty of Medicine, Safarik University, Kosice, Slovak Republic.

Abstract

AIMS AND OBJECTIVES:

To explore whether self-rated health acts as a potential mediator in the association between functional status and health-related quality of life in Parkinson's disease.

BACKGROUND:

Older persons (as most patients with Parkinson's disease are) who reported poor self-rated health compared with those with excellent self-rated health were two-and-a-half times more likely to have experienced a decline in functional ability.

DESIGN:

Cross-sectional.

METHODS:

Socio-demographic and clinical data of the patients (n = 176) were obtained during a structured interview and from medical records. Functional status was measured with the Unified Parkinson's Disease Rating Scale (total score), self-rated health with the first item of the Short-Form 36-item Health Survey Questionnaire and health-related quality of life with the disease-specific questionnaire called the Parkinson's Disease Quality of Life Questionnaire-39. Multiple linear regression analyses and the Sobel test were employed to assess mediation.

RESULTS:

Self-rated health seems to have a mediating effect on the association between functional status and health-related quality of life. The Sobel test confirmed an indirect effect of functional status via self-rated health on health-related quality of life and showed a statistically significant indirect effect of functional status on health-related quality of life via self-rated health against the direct route without the mediator.

CONCLUSIONS:

Self-rated health partially mediates the deteriorating effect of functional status on health-related quality of life.

RELEVANCE TO CLINICAL PRACTICE:

Supportive and adaptation psychosocial intervention programmes leading to restored self-rated health may enhance the quality of life regardless of disability in Parkinson's disease.

© 2013 John Wiley & Sons Ltd.

KEYWORDS:

Parkinson's disease; functional status; health indicator; health-related quality of life; mediator; self-rated health

PMID:
24354845
[PubMed - in process]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Blackwell Publishing
    Loading ...
    Write to the Help Desk