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Schizophr Res. 2014 Jan;152(1):152-7. doi: 10.1016/j.schres.2013.11.019. Epub 2013 Dec 14.

Neighbourhood-level socio-environmental factors and incidence of first episode psychosis by place at onset in rural Ireland: the Cavan-Monaghan First Episode Psychosis Study [CAMFEPS].

Author information

  • 1Department of Psychiatry, College of Medicine, University of Dammam, Saudi Arabia; Cavan-Monaghan Mental Health Service, Cavan Hospital, Cavan, Ireland; Molecular & Cellular Therapeutics and 3U Partnership, Royal College of Surgeons in Ireland, Dublin, Ireland. Electronic address: omersami@hotmail.com.
  • 2Department of Psychiatry, University of Cambridge, Cambridge, UK.
  • 3Department of Geography and 3U Partnership, National University of Ireland Maynooth, Maynooth, Ireland.
  • 4Cavan-Monaghan Mental Health Service, Cavan Hospital, Cavan, Ireland; Department of Psychiatry and 3U Partnership, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland.
  • 5DETECT Early Psychosis Service, Blackrock, Co. Dublin, Ireland.
  • 6Cavan-Monaghan Mental Health Service, Cavan Hospital, Cavan, Ireland; Molecular & Cellular Therapeutics and 3U Partnership, Royal College of Surgeons in Ireland, Dublin, Ireland.

Abstract

BACKGROUND:

Little is known about associations between the social environment and risk for psychosis within rural settings. This study sought to investigate whether such associations exist within a rural context using a prospective dataset of unusual epidemiological completeness.

METHOD:

Using the Cavan-Monaghan First Episode Psychosis Study database of people aged 16 years and older, both ecological analyses and multilevel modelling were applied to investigate associations between incidence of psychosis by place at onset and socio-environmental risk factors of material deprivation, social fragmentation and urban-rural classification across electoral divisions.

RESULTS:

The primary finding was an association between more deprived social contexts and higher rates of psychotic disorder, after adjustment for age and sex [all psychoses: incidence rate ratio (IRR)=1.12, 95% CI (1.03-1.23)].

CONCLUSIONS:

These findings support an association between adverse socio-environmental factors and increase in risk for psychosis by place at onset within a predominantly rural environment. This study suggests that social environmental characteristics may have an impact on risk across the urban-rural gradient.

Copyright © 2013 The Authors. Published by Elsevier B.V. All rights reserved.

KEYWORDS:

Environmental factors; First episode psychosis; Place at onset; Rurality; Social context

PMID:
24342585
[PubMed - indexed for MEDLINE]
PMCID:
PMC3906531
Free PMC Article
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