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Clin Microbiol Infect. 2014 Jan;20 Suppl 1:1-55. doi: 10.1111/1469-0691.12427.

ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gram-negative bacteria in hospitalized patients.

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  • 1Division of Infectious Diseases, Department of Internal Medicine I, Tübingen University Hospital, Tübingen, Germany.

Abstract

Healthcare-associated infections due to multidrug-resistant Gram-negative bacteria (MDR-GNB) are a leading cause of morbidity and mortality worldwide. These evidence-based guidelines have been produced after a systematic review of published studies on infection prevention and control interventions aimed at reducing the transmission of MDR-GNB. The recommendations are stratified by type of infection prevention and control intervention and species of MDR-GNB and are presented in the form of 'basic' practices, recommended for all acute care facilities, and 'additional special approaches' to be considered when there is still clinical and/or epidemiological and/or molecular evidence of ongoing transmission, despite the application of the basic measures. The level of evidence for and strength of each recommendation, were defined according to the GRADE approach.

© 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.

KEYWORDS:

Acinetobacter; Burkholderia; Enterobacteriaceae; Pseudomonas; Stenotrophomonas; extended-spectrum β-lactamase; guideline; infection control; multidrug-resistant Gram-negative; outbreak

PMID:
24329732
[PubMed - indexed for MEDLINE]
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