Send to:

Choose Destination
See comment in PubMed Commons below
Acta Biomater. 2014 Mar;10(3):1050-63. doi: 10.1016/j.actbio.2013.11.015. Epub 2013 Dec 7.

Ability of new obturation materials to improve the seal of the root canal system: a review.

Author information

  • 1Department of Stomatology, Fuzhou Dongfang Hospital, Fuzhou, China.
  • 2Department of Prosthodontics, School of Stomatology, Fourth Military Medical University, Xi'an, China.
  • 3Department of Stomatology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
  • 4North Shore Endodontics, North Vancouver, British Columbia, Canada.
  • 5UNIGRANRIO, School of Dentistry, Rio de Janeiro, Brazil.
  • 6Department of Dental and Biomedical Material Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
  • 7Department of Prosthodontics, School of Stomatology, Fourth Military Medical University, Xi'an, China. Electronic address:
  • 8Department of Oral Biology, Georgia Regents University, Augusta, GA, USA.
  • 9Department of Endodontics, Georgia Regents University, Augusta, GA, USA. Electronic address:


New obturation biomaterials have been introduced over the past decade to improve the seal of the root canal system. However, it is not clear whether they have really produced a three-dimensional impervious seal that is important for reducing diseases associated with root canal treatment. A review of the literature was performed to identify models that have been employed for evaluating the seal of the root canal system. In vitro and in vivo models are not totally adept at quantifying the seal of root canals obturated with classic materials. Thus, one has to resort to clinical outcomes to examine whether there are real benefits associated with the use of recently introduced materials for obturating root canals. However, there is no simple answer because endodontic treatment outcomes are influenced by a host of other predictors that are more likely to take precedence over the influence of obturation materials. From the perspective of clinical performance, classic root filling materials have stood the test of time. Because many of the recently introduced materials are so new, there is not enough evidence yet to support their ability to improve clinical performance. This emphasizes the need to translate anecdotal information into clinically relevant research data on new biomaterials.

Copyright © 2013 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.


Leakage models; Root canal; Root filling materials; Sealability; Treatment outcome

[PubMed - in process]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk