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Chem Commun (Camb). 2014 Feb 4;50(9):1092-4. doi: 10.1039/c3cc48398c.

Water-stable metal-organic frameworks with intrinsic peroxidase-like catalytic activity as a colorimetric biosensing platform.

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  • 1Hefei National Laboratory for Physical Sciences at the Microscale, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P.R. China.


Two iron(III)-based metal-organic frameworks (MOFs) are found to behave as efficient peroxidase mimics and catalyze the oxidation of different peroxidase substrates by H2O2 accompanied with significant color change in the solution. With these findings, a simple and sensitive colorimetric assay to detect H2O2 and ascorbic acid has been established.

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