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Physiol Rep. 2013 Oct;1(5):e00129. doi: 10.1002/phy2.129. Epub 2013 Oct 24.

Reticular activating system of a central pattern generator: premovement electrical potentials.

Author information

  • 1Institute of Physiology, Benemérita Universidad Autónoma de Puebla 14 Sur 6301, Col. San Manuel, Puebla, Puebla, CP 72570, México ; School of Biology, Benemérita Universidad Autónoma de Puebla 14 Sur 6301, Col. San Manuel, Puebla, Puebla, CP 72570, México.

Abstract

For the first time, here we characterize a bulbar reticular activating system (RAS) of neurons in decerebrate, deafferented and decerebellated cats producing a premovement electrical potential that we named obex slow potential (OSP). The OSP occurs about 0.8 ± 0.4 sec prior to the onset of a fictive-scratching-episode. Here, we describe two classes of bulbar neurons, off-on, which are silent but exhibit a 80 ± 56 Hz firing discharge at the beginning of (and during) the OSP, and on-off interneurons, with a 27 ± 14 Hz firing activity that stops at the beginning of (and during) the OSP. We suggest that these OSP-associated neurons belong to a descending RAS, which contributes to the activation of the spinal central pattern generators.

KEYWORDS:

Dorsal horn neurons; locomotion; scratch reflex; scratching; slow oscillations; spinal rehabilitation

PMID:
24303193
[PubMed]
PMCID:
PMC3841057
Free PMC Article
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