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Zh Nevrol Psikhiatr Im S S Korsakova. 2013;113(10 Pt 2):47-51.

[The CD100 semaphorin expression on peripheral blood T-lymphocytes in patients with relapsing-remitting multiple sclerosis].

[Article in Russian]


The expression of CD100 semaphorin by the intact peripheral blood T lymphocytes in multiple sclerosis (MS) has been studied. The level of middle florescence intensity (MFI) and the number of B-lymphocytes bearing CD72 were evaluated. There were significant differences in the level of CD100 in patients compared to healthy volunteers. These data suggest the use of semaphorin as a possible therapeutic target in pathological inflammation in MS.

[PubMed - indexed for MEDLINE]
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