Objective: To discuss the model of reasonable dissection extent of mediastinal lymph nodes in non-small cell lung cancer of diameter less than 2 cm.
Method: A study was carried on the clinical data of 192 patients with NSCLC of diameter less than 2 cm undergoing curative resection and mediastinal lymph nodes dissection,According to the size of tumor and the pathology quick report.
Results: The survival rates of patient was statistically significant difference (P < 0.01), prognostic factors included diameter of tumor, lymph node metastasis and visceral pleura invasion;51.7% mediastinal lymph node metastasis of superior lobe tumor, 28.8% transfering to subcarinal node; the mediastinal lymph node metastasis rate of adenocarcinoma was 32.2%, and squamous cell carcinoma was 15.4% (P = 0.0012) .
Conclusion: If the patient's cardiopulmonary function permitting, regardless of the size of focus, Regional mediastinal lymph nodal and subcarinal lymph nodal dissection should be routinely performed on patients with non-small cell lung cancer of diameter less than 2 cm, and improve survival rate.