A "turn-on" carbon nanotube-Ag nanoclusters fluorescent sensor for sensitive and selective detection of Hg2+ with cyclic amplification of exonuclease III activity

Chem Commun (Camb). 2014 Jan 21;50(6):747-50. doi: 10.1039/c3cc46716c. Epub 2013 Nov 29.

Abstract

With exonuclease III activity on DNA hybrids containing thymine-Hg(2+)-thymine, a label-free ultrasensitive "turn-on" fluorescent sensor involving "quenching" and "reappearing" processes based on a carbon nanotube-Ag nanoclusters system is demonstrated for amplified determination of Hg(2+).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chemistry Techniques, Analytical / instrumentation*
  • Cyclization
  • Exodeoxyribonucleases / chemistry*
  • Fluorescent Dyes / chemistry*
  • Limit of Detection
  • Mercury / analysis*
  • Nanotubes, Carbon / chemistry*
  • Silver / chemistry*

Substances

  • Fluorescent Dyes
  • Nanotubes, Carbon
  • Silver
  • Exodeoxyribonucleases
  • exodeoxyribonuclease III
  • Mercury