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Genome Biol. 2013 Nov 29;14(11):215. doi: 10.1186/gb4143.

Characterizing 5-methylcytosine in the mammalian epitranscriptome.

Abstract

The post-transcriptional modification 5-methylcytosine (m5C) occurs in a wide range of coding and non-coding RNAs. We describe transcriptome-wide approaches to capture the global m5C RNA methylome. We also discuss the potential functions of m5C in RNA and compare them to 6-methyladenosine modifications.

PMID:
24286375
[PubMed - in process]
PMCID:
PMC4053770
Free PMC Article

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