Display Settings:


Send to:

Choose Destination
J Med Imaging Radiat Oncol. 2013 Dec;57(6):652-6. doi: 10.1111/1754-9485.12054. Epub 2013 Apr 1.

CT-guided core biopsy of malignant lung lesions: how many needle passes are needed?

Author information

  • 1Department of Radiology, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.



The study aims to determine the number of needle pass in the CT-guided core needle biopsy (CNB) in making a diagnosis of pulmonary malignancy.


A total of 434 CNB records were retrospectively reviewed. The specimen obtained from each needle pass was put in a formalin container and then labelled for separate histopathological reporting. The patients were divided into five groups according to the total number of needle passes (n = 1, n = 2, n = 3, n = 4 and n ≥ 5). In each of the groups 2-4, it was analysed how many needle passes are required before a plateau in diagnostic yield is achieved.


CNB produced 283 true-positive and 23 false-negative diagnosis of malignancy. Cumulative sensitivity significantly (P < 0.05) increased between the first and second as well as the second and the third (if done) needle passes, but not between the third and fourth ones.


Three coaxial needle passes might be optimal in the diagnosis of lung malignancy.

© 2013 The Authors. Journal of Medical Imaging and Radiation Oncology © 2013 The Royal Australian and New Zealand College of Radiologists.


body CT; chest imaging; intervention; non-vascular interventional radiology

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Blackwell Publishing
    Loading ...
    Write to the Help Desk