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JAMA. 2013 Dec 11;310(22):2451-2. doi: 10.1001/jama.2013.281348.

Statin therapy for primary prevention of cardiovascular disease.

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  • 1Department of Noncommunicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.

Abstract

CLINICAL QUESTION:

Do statins reduce rates of cardiovascular events when used for primary prevention?

BOTTOM LINE:

When used for primary prevention, statins are associated with lower rates of all-cause mortality, major vascular events, and revascularizations compared with placebo. Statin therapy is not associated with increased rates of life-threatening adverse effects such as cancer.

PMID:
24276813
[PubMed - indexed for MEDLINE]
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