CARD9 mutations linked to subcutaneous phaeohyphomycosis and TH17 cell deficiencies

Xiaowen Wang; Wenyan Wang; Zhimiao Lin; Xiaolin Wang; Ting Li; Jin Yu; Wei Liu; Zhongsheng Tong; Yonghao Xu; Junling Zhang; Liping Guan; Lanlan Dai; Yong Yang; Wenling Han; Ruoyu Li

doi:10.1016/j.jaci.2013.09.033

CARD9 mutations linked to subcutaneous phaeohyphomycosis and TH17 cell deficiencies

J Allergy Clin Immunol. 2014 Mar;133(3):905-8.e3. doi: 10.1016/j.jaci.2013.09.033. Epub 2013 Nov 11.

Authors

Xiaowen Wang¹, Wenyan Wang², Zhimiao Lin³, Xiaolin Wang², Ting Li², Jin Yu¹, Wei Liu¹, Zhongsheng Tong⁴, Yonghao Xu⁵, Junling Zhang⁶, Liping Guan⁷, Lanlan Dai⁷, Yong Yang⁸, Wenling Han⁹, Ruoyu Li¹⁰

Affiliations

¹ Department of Dermatology, Peking University First Hospital, Beijing, China; Research Center for Medical Mycology, Peking University, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China.
² Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China; Peking University Center for Human Disease Genomics, Beijing, China; Key Laboratory of Medical Immunology, Ministry of Health, Beijing, China.
³ Department of Dermatology, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China.
⁴ Department of Dermatology, Center for Infectious Skin Diseases, Wuhan First Hospital, Wuhan, China.
⁵ Department of Dermatology, Qilu Hospital of Shandong University, Ji'nan, China.
⁶ Department of Dermatology, Tianjin Changzheng Hospital, Tianjin, China.
⁷ BGI-Shenzhen, Shenzhen, China.
⁸ Department of Dermatology, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China; Peking-Tsinghua Center for Life Sciences, Beijing, China.
⁹ Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China; Peking University Center for Human Disease Genomics, Beijing, China; Key Laboratory of Medical Immunology, Ministry of Health, Beijing, China. Electronic address: hanwl@bjmu.edu.cn.
¹⁰ Department of Dermatology, Peking University First Hospital, Beijing, China; Research Center for Medical Mycology, Peking University, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China. Electronic address: mycolab@126.com.

PMID: 24231284
DOI: 10.1016/j.jaci.2013.09.033

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
CARD Signaling Adaptor Proteins / genetics*
Female
Humans
Male
Middle Aged
Mutation*
Phaeohyphomycosis / genetics*
Phaeohyphomycosis / immunology
Th17 Cells / immunology*

Substances

CARD Signaling Adaptor Proteins
CARD9 protein, human