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Psychiatr Clin North Am. 2013 Dec;36(4):577-96. doi: 10.1016/j.psc.2013.08.012. Epub 2013 Oct 6.

What is the role of alternative treatments in late-life depression?

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  • 1Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 1 Bowdoin Square, 6th Floor, Boston, MA 02114, USA. Electronic address:


Late-life depression remains challenging to treat. One major limitation to treatment is the concern over medication-related side effects to which the elderly are especially vulnerable. Also, because many elderly people are already taking multiple medications for medical conditions, there is the concern over drug-drug interactions. This article reviews various complementary and alternative medicine interventions for late-life depression, including natural remedies, exercise, yoga, tai chi, massage therapy, music therapy, and religion and spirituality.

Copyright © 2013 Elsevier Inc. All rights reserved.


Exercise; Late-life depression; Massage therapy; Music therapy; Natural remedies; Spirituality; Tai chi; Yoga

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