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Semin Thorac Cardiovasc Surg. 2013 Summer;25(2):87-94. doi: 10.1053/j.semtcvs.2013.05.002.

Women and lung cancer: what is new?

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  • 1Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.

Abstract

In the last 20 years, there has been an increased focus on gender differences in health and disease. The earliest studies of lung cancer enrolled mainly men, as the incidence of lung cancer among women was exceedingly low. As social patterns changed around World War II and women began to smoke more, the epidemiology of lung cancer has changed. The higher percentage of lung cancer in nonsmoking women as compared with nonsmoking men suggests that lung cancer behaves differently in women. Studies of lung cancer in women indicate that there are differences in risk factors, histology, pathophysiology, treatment outcomes, and prognosis as compared with men. The purpose of this review is to provide a concise summary of the literature on lung cancer as it pertains to women, with an emphasis on new areas of research and treatment options.

Copyright © 2013 Elsevier Inc. All rights reserved.

KEYWORDS:

genetic mutations; lung cancer; risk factors; women

PMID:
24216523
[PubMed - indexed for MEDLINE]
PMCID:
PMC3827695
Free PMC Article
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