Send to:

Choose Destination
See comment in PubMed Commons below
J Am Soc Mass Spectrom. 1995 Nov;6(11):1030-6. doi: 10.1016/1044-0305(95)00504-8.

Characterization of the C3H 6O (+·) ion from 2-methoxyethanol. Mixture analysis by dissociation and neutralization-reionization.

Author information

  • 1Department of Chemistry, The University of Akron, 44325-3601, Akron, Ohio.


The C3H6O(+·) ion formed upon the dissociative ionization of 2-methoxyethanol is identified by a combination of several tandem mass spectrometry methods, including metastable ion (MI) characteristics, collisionally activated dissociation (CAD), and neutralization-reionization mass spectrometry (NRMS). The experimental data conclusively show that 2-methoxyethanol molecular ion, namely, HOCH2CH2OCH 3 (+·) , loses H2O to yield mainly the distonic radical ion ·CH2CH2OCH 2 (+) along with a smaller amount of ionized methyl vinyl ether, namely, CH2=CHOCH 3 (+·) . Ring-closed products, such as the oxetane or the propylene oxide ion are not observed. The proportion of ·CH2CH2OCH 2 (+) increases with decreasing internal energy of the 2-methoxyethanol ion, which indicates a lower critical energy for the pathway leading to this product than for the competitive generation of CH2=CHOCH 3 (+·) . The present study also uses MI, CAD, and NRMS data to assess the structure of the distonic ion(+) (CH3)CHOCH2· (ring-opened ionized propylene oxide) and evaluate its isomerization proclivity toward the methyl vinyl ether ion.

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk