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Ann Ophthalmol. 1986 Feb;18(2):52-8.

Fundus-iris fluorescein angiography: evaluation of its use in the diagnosis of rubeosis iridis.

Erratum in

  • Ann Ophthalmol 1986 Apr;18(4):155.


Fundus-iris fluorescein angiography is a technique that allows iris angiography and retinal angiography to be performed simultaneously, using a single injection of dye and a standard retinal fundus camera. We analyzed the ability of this technique to detect rubeosis iridis. In a study of 200 randomly selected angiograms on 400 eyes, the technique was able to detect 97.2% of all eyes with rubeosis iridis (sensitivity), with a false-positive rate of 1%. In 26 eyes (36.6% of all eyes with rubeosis), it was able to detect rubeosis prior to the development of vessels visible by slit-lamp biomicroscopy. The test was able to correctly identify 98.8% of the eyes without rubeosis (specificity), with a false-negative rate of 0.5%. This technique can be performed routinely as part of retinal angiography.

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