Send to:

Choose Destination
See comment in PubMed Commons below
Biomed Opt Express. 2013 Sep 3;4(10):1909-24. doi: 10.1364/BOE.4.001909. eCollection 2013.

Blood flow velocity quantification using split-spectrum amplitude-decorrelation angiography with optical coherence tomography.

Author information

  • 1Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, CA 90089, USA.


The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was recently developed as a method for imaging blood flow in the human retina without the use of phase information. In order to enable absolute blood velocity quantification, in vitro phantom experiments are performed to correlate the SSADA signal at multiple time scales with various preset velocities. A linear model relating SSADA measurements to absolute flow velocities is derived using the phantom data. The operating range for the linear model is discussed along with its implication for velocity quantification with SSADA in a clinical setting.


(170.3880) Medical and biological imaging; (170.4470) Ophthalmology; (170.4500) Optical coherence tomography

Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk