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Ocul Immunol Inflamm. 2014 Oct;22(5):394-7. doi: 10.3109/09273948.2013.845230. Epub 2013 Oct 21.

Cryptic uveitis in a patient with morning glory syndrome.

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  • 1Stoke Mandeville Hospital, Department of Ophthalmology , Aylesbury , UK.

Abstract

BACKGROUND:

A 71-year-old female presented on 3 occasions with escalating pain in a congenitally blind eye. Examination revealed hypertensive uveitis with morning glory optic disc dysplasia and absence of a crystalline lens. There was no previous intraocular surgery or trauma. Intensive anti-hypertensive agents and topical steroids did not control intraocular pressure (IOP) or inflammation.

RESULTS:

Dilated fundus examination on the third clinical review revealed a luxated cataractous lens on the retina. Pars plana vitrectomy and fragmatome lensectomy controlled inflammation and IOP, with resolution of ocular pain.

DISCUSSION:

This is an exceptional case of phacogenic uveitis with secondary glaucoma occurring years after spontaneous crystalline lens luxation in a patient with morning glory syndrome. The embryological pathogenesis of morning glory syndrome and the significance of accelerated cataractogenesis and zonular weakness are discussed. Hypertensive uveitis with unexplained absence of a crystalline lens in a blind eye must prompt suspicion of delayed phacogenic uveitis following asymptomatic lens luxation.

KEYWORDS:

Lens luxation; morning glory syndrome; optic dysplasia; phacogenic glaucoma; phacogenic uveitis; zonular weakness

PMID:
24143921
[PubMed - indexed for MEDLINE]
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