Send to:

Choose Destination
See comment in PubMed Commons below
Ocul Immunol Inflamm. 2014 Oct;22(5):394-7. doi: 10.3109/09273948.2013.845230. Epub 2013 Oct 21.

Cryptic uveitis in a patient with morning glory syndrome.

Author information

  • 1Stoke Mandeville Hospital, Department of Ophthalmology , Aylesbury , UK.



A 71-year-old female presented on 3 occasions with escalating pain in a congenitally blind eye. Examination revealed hypertensive uveitis with morning glory optic disc dysplasia and absence of a crystalline lens. There was no previous intraocular surgery or trauma. Intensive anti-hypertensive agents and topical steroids did not control intraocular pressure (IOP) or inflammation.


Dilated fundus examination on the third clinical review revealed a luxated cataractous lens on the retina. Pars plana vitrectomy and fragmatome lensectomy controlled inflammation and IOP, with resolution of ocular pain.


This is an exceptional case of phacogenic uveitis with secondary glaucoma occurring years after spontaneous crystalline lens luxation in a patient with morning glory syndrome. The embryological pathogenesis of morning glory syndrome and the significance of accelerated cataractogenesis and zonular weakness are discussed. Hypertensive uveitis with unexplained absence of a crystalline lens in a blind eye must prompt suspicion of delayed phacogenic uveitis following asymptomatic lens luxation.


Lens luxation; morning glory syndrome; optic dysplasia; phacogenic glaucoma; phacogenic uveitis; zonular weakness

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis
    Loading ...
    Write to the Help Desk