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J Allergy Clin Immunol. 2013 Dec;132(6):1287-92. doi: 10.1016/j.jaci.2013.08.043. Epub 2013 Oct 17.

Advances in in vitro diagnostics in allergy, asthma, and immunology in 2012.

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  • 1Institute of Laboratory Medicine, Philipps-Universit√§t Marburg, Marburg, Germany. Electronic address: renzh@med.uni-marburg.de.


Laboratory tests play an increasing role in risk assessment, diagnostics, and disease monitoring. Great advances have been achieved lately, particularly in the field of clinical immunology and allergy. These include neonatal screening of immunodeficiencies and asthma biomarkers and investigation into the role of recombinant allergens in in vitro testing. The latter area has implications for the diagnostics of food allergy, pollen-induced allergies, asthma, and insect allergies.

Copyright © 2013 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.


CCD; CVID; Carbohydrate determinant; Common variable immunodeficiency; Feno; Fraction of exhaled nitric oxide; GCR; Glucocorticoid receptor; Immunodeficiencies; SCID; SLIT; Severe combined immunodeficiency; Sublingual immunotherapy; T-cell receptor excision circle; TREC; WDEIA; Wheat-dependent, exercise-induced anaphylaxis; food allergy; insect venom allergies; neonatal screening; recombinant allergens; rhinitis

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