Fast grating-based X-ray phase-contrast tomosynthesis

Annu Int Conf IEEE Eng Med Biol Soc. 2013:2013:2320-3. doi: 10.1109/EMBC.2013.6610002.

Abstract

As an imaging technique with low radiation dose and improved contrast, digital x-ray tomosynthesis is widely used in clinical diagnoses. Based on the superior capability of x-ray phase-contrast imaging (PCI) techniques for imaging low density materials, the combination of X-ray tomosynthesis and PCI can potentially provide higher efficiency in the detection of soft tissues. The goal of this work was to develop a fast imaging method for phase-contrast tomosynthesis, called fast grating-based phase-contrast tomosynthesis (GPC-Tomo), which integrates tomosynthesis with a grating-based PCI technique. Following the interlaced phase-stepping (PS) data collection method, which is much faster than conventional PS method, we propose a novel image reconstruction method called inner-focusing (IF) reconstruction for the fast GPC-Tomo. The proposed IF reconstruction method was validated by real experiments and the results suggested its effectiveness in achieving a fast GPC-Tomo.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Humans
  • Imaging, Three-Dimensional
  • Mice, Inbred C57BL
  • Radiation Dosage
  • Radiographic Image Enhancement / methods*