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Mar Drugs. 2013 Sep 30;11(10):3601-16. doi: 10.3390/md11103601.

Advances in the study of the structures and bioactivities of metabolites isolated from mangrove-derived fungi in the South China Sea.

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  • 1Department of Neurosurgery and Pituitary Tumour Center, the First Affiliated Hospital of Sun Yat-sen University, No. 74, Zhongshan Road 2, Guangzhou 510080, China. zhuyongh@mail.sysu.edu.cn.


Many metabolites with novel structures and biological activities have been isolated from the mangrove fungi in the South China Sea, such as anthracenediones, xyloketals, sesquiterpenoids, chromones, lactones, coumarins and isocoumarin derivatives, xanthones, and peroxides. Some compounds have anticancer, antibacterial, antifungal and antiviral properties, but the biosynthesis of these compounds is still limited. This review summarizes the advances in the study of secondary metabolites from the mangrove-derived fungi in the South China Sea, and their biological activities reported between 2008 and mid-2013.

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