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Head Neck Pathol. 2014 Jun;8(2):225-8. doi: 10.1007/s12105-013-0492-6. Epub 2013 Sep 27.

Extraskeletal Ewing's sarcoma arising in the larynx.

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  • 1Department of Pathology H179, Penn State Hershey Medical Center, Hershey, PA, 17033, USA,


Extraskeletal Ewing's sarcoma (EES), or primitive neuroectodermal tumor, is an uncommon neoplasm with low incidence in the head and neck. Occurrences in the larynx are even more exceptional with only two previous reported cases of EES arising from the larynx. We report the case of a 45-year-old woman with a laryngeal Ewing's sarcoma treated with chemotherapy with radiotherapy to follow. Here we describe the histology, molecular diagnosis and treatment of this unusual tumor.

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