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J Am Acad Dermatol. 2013 Dec;69(6):965-71. doi: 10.1016/j.jaad.2013.06.045. Epub 2013 Sep 17.

Evaluation of microfocused ultrasound with visualization for lifting, tightening, and wrinkle reduction of the décolletage.

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  • 1Goldman, Butterwick, Fitzpatrick, Groff, and Fabi, Cosmetic Laser Dermatology, San Diego, California; University of California, San Diego, California. Electronic address:



Laxity and rhytides are manifestations of photodamage on the chest.


We sought to evaluate efficacy and safety of microfocused ultrasound with visualization treatment of décolletage laxity and rhytides.


In all, 24 subjects with moderate to severe rhytides, as measured by a validated 5-point photonumeric scale (Fabi/Bolton Chest Wrinkle Scale), received microfocused ultrasound with visualization treatment. Efficacy was measured at 90 and 180 days by the Fabi/Bolton Chest Wrinkle Scale, mid-clavicular to nipple distance, masked assessment, Physician and Subject Global Aesthetic Improvement Scales, and patient satisfaction. Adverse events were recorded.


Rhytides improved over time (P < .0001), with 46% and 62% of subjects showing a 1- to 2-point improvement at days 90 and 180, respectively. Mean (SD) mid-clavicular to nipple distance decreased (P < .0001), from 20.9 (1.57) cm to 19.8 (1.50) cm and 19.5 (1.59) cm, at days 90 and 180, respectively. At day 90, 100% were improved by Subject Global Aesthetic Improvement Scale score (P < .0001) and 96% were improved by Physician Global Aesthetic Improvement Scale score (P < .0001), with similar findings at day 180. All subjects were satisfied or very satisfied at day 90, with similar results at day 180. Improvement by masked assessment at day 90 was 71%.


Single-center study, small sample size, and only Fitzpatrick skin types I and II enrolled were limitations.


There was appreciable efficacy and patient satisfaction after a single microfocused ultrasound with visualization treatment in wrinkle reduction and lifting of the décolletage.

Copyright © 2013 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.


FBCWS; Fabi/Bolton Chest Wrinkle Scale; MFU-V; PGAIS; PIH; Physician Global Aesthetic Improvement Scale; SGAIS; Subject Global Aesthetic Improvement Scale; chest; décolletage; microfocused ultrasound with visualization; photoaging; postinflammatory hyperpigmentation; tightening; wrinkles

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