Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Am J Emerg Med. 2013 Nov;31(11):1586-90. doi: 10.1016/j.ajem.2013.08.009. Epub 2013 Sep 16.

How to differentiate spontaneous intramural intestinal hemorrhage from acute mesenteric ischemia.

Author information

  • 1Department of Emergency Medicine, Taichung Veterans General Hospital, Taichung 407, Taiwan; Emergency Medicine, College of Medicine, National Yang-Ming University, Taipei 112, Taiwan.

Abstract

OBJECTS:

The purpose of our study was to assess the diagnostic values of laboratory tests to differentiate spontaneous intramural intestinal hemorrhage (SIIH) from acute mesenteric ischemia (AMI) after abdominal computed tomography (CT) survey in the emergency department (ED).

METHOD:

We retrospectively included 76 patients diagnosed SIIH or AMI after abdominal CT.

RESULTS:

The mean ages of 28 SIIH patients and 48 AMI patients were 75.9 ± 13.7 years and 75.8 ± 11.6 years, respectively. Patients with SIIH had significantly higher rate of Coumadin use (P < .001) and localized tenderness (P < .05). In laboratory findings, SIIH patients had prolonged prothrombin time (PT) (83.6 ± 30.0 vs. 13.4 ± 3.2, P < .001), lower blood urea nitrogen (P < .05), lower creatinine (P < .05), and lower creatine kinase (P < .05). Prolonged PT showed good discriminative value to differentiate acute abdomen patients with SIIH from AMI after abdominal CT, with an area under the receiver operating characteristic curve of 0.980 (95% confidence interval, 0.918-0.998; P < .0001). Prolonged PT cut-off value of ≧22.5 seconds had a sensitivity of 92.9% and a specificity of 100%. Logistic regression analysis identified prolonged PT as an independent predictor of SIIH (odds ratio, OR, 22.2; P = .007).

CONCLUSION:

Abdominal pain patients with either SIIH or AMI are rare in the ED, but abdominal CT sometimes cannot help to differentiate them due to similar CT findings. Prolonged PT might help emergency physicians and surgeons differentiate SIIH from AMI in such cases.

© 2013.

PMID:
24051008
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk