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Thromb Res. 2013 Oct;132(4):403-7. doi: 10.1016/j.thromres.2013.07.027. Epub 2013 Aug 13.

The clinical implications of ADAMTS13 function: the perspectives of haemostaseologists.

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  • 1Centre for Haemostasis & Thrombosis, Guy's & St Thomas' NHS Foundation Trust, London. Electronic address: savita.rangarajan@gstt.nhs.uk.


Apart from TTP, ADAMTS13 may be an important player in those conditions where Von Willebrand Factor and the Platelet Glycoprotein GP Ib axis have a part to play in the pathogenesis. This includes stroke, myocardial infarction, sepsis and inflammatory condition. This article reviews the literature in these conditions.

© 2013.

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