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PLoS One. 2013 Sep 3;8(9):e73180. doi: 10.1371/journal.pone.0073180. eCollection 2013.

Validation of the French version of the World Health Organization quality of life HIV instrument.

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  • 1Institut de Recherche Expérimentale et Clinique (IREC), Pôle de Pneumologie, ENT & Dermatologie, Université Catholique de Louvain, Brussels, Belgium ; Service de Pneumologie, Cliniques universitaires Saint-Luc, Brussels, Belgium ; Département de Médecine Physique et Réadaptation, Cliniques universitaires Saint-Luc, Brussels, Belgium.



Quality of life is a key element in the follow-up of people living with HIV/AIDS. The main purpose of this study was to validate the French version of the WHOQOL-HIV instrument by comparing this instrument to a generic questionnaire. The second objective was to test the reproducibility of this questionnaire.


The WHOQOL-HIV and SF-36 questionnaires were filled out by 50 patients on two separate occasions with a time interval of 2 weeks. The internal consistency, validity and reliability of the WHOQOL-HIV were evaluated.


The internal consistency was acceptable for the different domains, with Cronbach's alpha ranging from 0.937 to 0.944. The facet-domain correlations were all statistically significant (p<0.001). There was a correlation between the domains from the WHOQOL-HIV and SF-36 questionnaires, with coefficients ranging from 0.349 to 0.763 (p<0.05 for all), except for the Spirituality domain. The test-retest reliability was suitable for all domains and facets, with statistically significant intra-class coefficients between 0.615 and 0.931.


This study demonstrated that the French translation of the WHOQOL-HIV instrument is a valid and reproducible tool for the evaluation of the quality of life for HIV-infected patients.

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